How to store CABLIVI


  • Store CABLIVI in a refrigerator at 36°F to 46°F (2°C to 8°C) in its original packaging to protect it from light
  • You may also store unopened vials of CABLIVI at room temperature, up to 86°F (30°C), for a single period of up to 2 months, but not beyond the expiration date
  • Use the mixed CABLIVI solution immediately after mixing. The mixed CABLIVI solution can be stored for up to 4 hours in the refrigerator at 36°F to 46°F (2°C to 8°C)
  • Keep the CABLIVI carton and supplies out of the reach of children


  • Do not return CABLIVI to the refrigerator after storage at room temperature
  • Do not freeze
  • Do not use CABLIVI if you notice any particles in the solution or discoloration prior to administration
  • Do not use CABLIVI after the expiration date stated on the label and carton after “EXP.” CABLIVI expires on the last day of the month in the expiration date on the label and carton
  • Do not throw away any medication, syringes, or needles with your household trash. Ask your pharmacist how to dispose of any CABLIVI you’re unable to use, or dispose of CABLIVI in a sharps container (container that is filled with medical needles after they are used). This will help protect you and the environment


Who should not take CABLIVI?

Do not take CABLIVI if you’ve had an allergic reaction to caplacizumab-yhdp or to any of the ingredients in CABLIVI.

What should I tell my healthcare team before starting CABLIVI?

Tell your doctor if you have a medical condition including if you have a bleeding disorder. Tell your doctor about any medicines you take.

Talk to your doctor before scheduling any surgery, medical or dental procedure.

What are the possible side effects of CABLIVI?

CABLIVI can cause severe bleeding. In clinical studies, severe bleeding adverse reactions of nosebleed, bleeding from the gums, bleeding in the stomach or intestines, and bleeding from the uterus were each reported in 1% of subjects. Contact your doctor immediately if excessive bleeding or bruising occur.

You may have a higher risk of bleeding if you have a bleeding disorder (i.e. hemophilia) or if you take other medicines that increase your risk of bleeding such as anti-coagulants.

CABLIVI should be stopped for 7 days before surgery or any medical or dental procedure. Talk to your doctor before you stop taking CABLIVI.

The most common side effects include nosebleed, headache and bleeding gums.

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of CABLIVI. Call your doctor for medical advice about side effects.


What is CABLIVI?

CABLIVI (caplacizumab-yhdp) is a prescription medicine used for the treatment of adults with acquired thrombotic thrombocytopenic purpura (aTTP), in combination with plasma exchange and immunosuppressive therapy.

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TTP=thrombotic thrombocytopenic purpura.