Living with aTTP

While some people may only experience one aTTP episode, others may have more

An aTTP episode is an acute episode. This means it happens suddenly and lasts a short time with treatment. However, some patients who had one aTTP episode will have another. A study of the medical records of 21 people with aTTP over 30 years showed that 90% experienced another episode over their lifetime. This is called a recurrence.

Patient at home

It is important to be aware of and watch for any aTTP symptoms. If you think that you have signs and symptoms of an aTTP episode, talk to your doctor or visit your local emergency room right away.

Symptoms can include:

  • Bleeding from the gums or nose
  • Purple bruises (known as purpura) and/or red or purple dots (known as petechiae) on the skin
  • Blood in urine
  • Stomach pain
  • Chest pain
  • Seizures
  • Headaches, confusion, or distorted vision
  • Tiredness and jaundice (a yellowing of the skin and eyes)

IMPORTANT SAFETY INFORMATION

Who should not take CABLIVI?

Do not take CABLIVI if you’ve had an allergic reaction to caplacizumab-yhdp or to any of the ingredients in CABLIVI.

What should I tell my healthcare team before starting CABLIVI?

Tell your doctor if you have a medical condition including if you have a bleeding disorder. Tell your doctor about any medicines you take.

Talk to your doctor before scheduling any surgery, medical or dental procedure.

What are the possible side effects of CABLIVI?

CABLIVI can cause severe bleeding. In clinical studies, severe bleeding adverse reactions of nosebleed, bleeding from the gums, bleeding in the stomach or intestines, and bleeding from the uterus were each reported in 1% of subjects. Contact your doctor immediately if excessive bleeding or bruising occur.

You may have a higher risk of bleeding if you have a bleeding disorder (i.e. hemophilia) or if you take other medicines that increase your risk of bleeding such as anti-coagulants.

CABLIVI should be stopped for 7 days before surgery or any medical or dental procedure. Talk to your doctor before you stop taking CABLIVI.

The most common side effects include nosebleed, headache and bleeding gums.

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of CABLIVI. Call your doctor for medical advice about side effects.

INDICATION

What is CABLIVI?

CABLIVI (caplacizumab-yhdp) is a prescription medicine used for the treatment of adults with acquired thrombotic thrombocytopenic purpura (aTTP), in combination with plasma exchange and immunosuppressive therapy.

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