How is aTTP/iTTP* treated?
Potential aTTP/iTTP treatments are given with 2 major therapeutic goals:
- Treat low platelet count
- Protect from autoimmune response against ADAMTS13 enzymes
Your doctor will decide what treatment is best for you. It is common for aTTP/iTTP to be treated with plasma exchange and immunosuppressive therapy.
Alex, real patient. Individual results may vary.
Alex is being compensated by Sanofi.
Plasma exchange (sometimes abbreviated as PEX/TPE or called apheresis or plasmapheresis)
- Plasma exchange is a procedure that removes and replaces a person's blood plasma.
- This process helps clean your blood by removing things you have too much of (such as immune cells) and adding things you have too little of (such as ADAMTS13 enzymes and platelets).
- This treatment usually takes a couple of hours each day and may need to be done for several days or weeks.
Immunosuppressive therapy is a medicine that helps decrease the activity of your immune system, which is overactive during an episode of aTTP/iTTP.
Prescription medicine designed specifically for aTTP/iTTP
CABLIVI is approved to treat adults with aTTP/iTTP. It is meant to prevent your body from forming blood clots, and it works together with plasma exchange and immunosuppressive therapy.
Meet your healthcare team
Below are some of the professionals you may come across during treatment. Because everyone's experience with aTTP/iTTP is different, you may not have the same healthcare team.
In the hospital
Hematologist (or hematologist-oncologist)
A hematologist is a doctor who focuses on diagnosing, treating, and/or preventing blood disorders. A hematologist-oncologist is a doctor who focuses on both blood disorders and blood cancer.
Your hematologist is likely to be your main point of contact when you're being treated for aTTP/iTTP in the hospital. They will talk to you about aTTP/iTTP and your treatment plan.
A nephrologist is a doctor who focuses on conditions that affect the kidneys.
Nephrologists administer plasma exchange at some hospitals. If that's the case for your hospital, your nephrologist may be your main point of contact. They will likely work with a hematologist for your treatment.
Pathologist/Transfusion Medicine Specialist
A pathologist studies the causes and effects of conditions and may administer plasma exchange. A transfusion medicine specialist is knowledgeable about all aspects of blood banking and transfusion medicine. A pathologist can also specialize in transfusion medicine.
Your pathologist or transfusion medicine specialist may work with your hematologist or nephrologist to help find the cause of your symptoms.
A nurse works with doctors and other healthcare team members to care for people being treated.
Your nurse may assist you throughout treatment during your time at the hospital and when it's time for you to go home.
After the hospital
After leaving the hospital, you should continue to check in with your hematologist as often as they recommend.
Primary Care Physician
Your primary care physician may want to see you regularly to see how you're doing.
Your nurse may assist with your treatment after you've left the hospital.
Specialty Pharmacy Services
The specialty pharmacy coordinates direct-to-home shipment of CABLIVI for a seamless transition upon discharge.